Cotton bollworm, Helicoverpa armigera (Lep. Noctouidae) is one of the key pests in cotton fields in Golestan province. In some areas the feeding of buds, bolls of cotton and cotton products will be damaged. In this survey a new insecticide product, karvin were tested on cotton bollworm and important natural enemies, coccinellids, chrysopids and braconid in the field of cotton in Golestan province during2013 – 2014. Six treatments ( larvin 1 kg/ha , karvin 1 lit/ha, karvin 1.5 lit/ha, karvin 2 lit/ha,avant 250 ml/ha and chek) with four replications were tested at a complete randomized block design in Gorgan. Sampling was done before and 3, 5, 7, 10 and 15 days after spraying. The mortality was calculated using Tilton- Hendrson formula were compared by Duncan s multiple rang test. The results revealed that average percentage of the best treatments for poison Karvin 1.5 lit/ha in 7 to 10 days after spraying with 81.25 – 100 % cotton bollworm and impact on the level 5 % were in group A and other treatments karvin 2 lit/ha with 71.88%, larvin 1 kg/ha 61.50 % and avant 250 ml/ha 56.25 % were the next groups. Therefore, we recommended the new insecticide Karvin with no significant adverse for controlling of cotton bollworn for the next year.